Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 6/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6872756 | 0.98 | DNM1 (0.63) | DNM1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL8399166 | 0.98 | DNM1 (0.63) | DNM1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL11654487 | 0.96 | DNM1 (0.59) | DNM1HTTMEN1KMT2AALDH1A1 | |
| SCHEMBL10003957 | 0.90 | DNM1 (0.55) | DNM1HTT | |
| SCHEMBL10943226 | 0.89 | — | — | |
| Sulfuric Acid SCHEMBL16735342 | 0.87 | DNM1 (0.52) | DNM1HTTTSHRCA1CA2 | |
| Sulfuric Acid SCHEMBL130672 | 0.87 | DNM1 (0.52) | DNM1HTTTSHRCA1CA2 | |
| SCHEMBL10004090 | 0.81 | DNM1 (0.44) | DNM1HTTALDH1A1CA1CA2 | |
| SCHEMBL8390821 | 0.79 | DNM1 (0.50) | DNM1HTTMEN1KMT2ATSHR | |
| SCHEMBL7777213 | 0.79 | DNM1 (0.50) | DNM1HTTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115368264-A | Compound, liposome and application thereof | 北京理工大学 | 2022-11-22 | — | — | CN | disclosed |