Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 9/20 | 0.44 |
| ▸ | CA2 | P00918 | 9/20 | 0.44 |
| ▸ | CA9 | Q16790 | 8/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.44 |
| ▸ | CA3 | P07451 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA5A | P35218 | 2/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL130672 | 1.00 | DNM1 (0.52) | DNM1TP53CA1CA2CA9 | |
| SCHEMBL8399166 | 0.89 | DNM1 (0.63) | DNM1CA1CA2CA9HTT | |
| SCHEMBL6872756 | 0.89 | DNM1 (0.63) | DNM1CA1CA2CA9HTT | |
| Bromide SCHEMBL30017166 | 0.87 | DNM1 (0.61) | DNM1CA1CA2CA9HTT | |
| SCHEMBL11654487 | 0.87 | DNM1 (0.59) | DNM1CA1CA2CA9HTT | |
| SCHEMBL10003957 | 0.81 | DNM1 (0.55) | DNM1HTTTLR2 | |
| Sulfuric Acid SCHEMBL31520303 | 0.81 | TP53 (0.48) | DNM1TP53CA1CA2CA9 | |
| SCHEMBL10943226 | 0.80 | — | — | |
| SCHEMBL27741674 | 0.80 | CA1 (0.41) | DNM1TP53CA1CA2CA9 | |
| SCHEMBL17817246 | 0.80 | CA1 (0.41) | DNM1TP53CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2876154-B1 | AN ADHESIVE DETERGENT AND/OR PERFUMING COMPOSITION | BOLTON MANITOBA SPA (IT) | 2019-07-24 | — | — | EP | claimed |
| US-20150148281-A1 | ADHESIVE DETERGENT AND/OR PERFUMING COMPOSITION | BOLTON MANITOBA S.P.A. (IT) | 2015-05-28 | — | — | US | claimed |
| EP-2876154-A1 | AN ADHESIVE DETERGENT AND/OR PERFUMING COMPOSITION | Bolton Manitoba SpA (IT) | 2015-05-27 | — | — | EP | claimed |
| EP-2876154-B1 | AN ADHESIVE DETERGENT AND/OR PERFUMING COMPOSITION | BOLTON MANITOBA SPA (IT) | 2019-07-24 | — | — | EP | disclosed |
| US-20150148281-A1 | ADHESIVE DETERGENT AND/OR PERFUMING COMPOSITION | BOLTON MANITOBA S.P.A. (IT) | 2015-05-28 | — | — | US | disclosed |
| EP-2876154-A1 | AN ADHESIVE DETERGENT AND/OR PERFUMING COMPOSITION | Bolton Manitoba SpA (IT) | 2015-05-27 | — | — | EP | disclosed |