Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4833930 | 0.81 | TLR7 (0.36) | TLR7LMNAGABRA1GABRG2GABRB3 | |
| SCHEMBL20489429 | 0.74 | LMNA (0.41) | HTTKMT2ALMNAGABRA1GABRG2 | |
| SCHEMBL28051797 | 0.74 | HTT (0.46) | HTTKMT2ATLR7LMNA | |
| SCHEMBL19761022 | 0.71 | LMNA (0.42) | HTTKMT2ALMNAGABRA1GABRG2 | |
| SCHEMBL30019041 | 0.71 | NOS2 (0.44) | HTTKMT2A | |
| SCHEMBL23534521 | 0.70 | KMT2A (0.46) | HTTKMT2ATLR7LMNA | |
| SCHEMBL16680007 | 0.70 | MAPK1 (0.36) | TLR7LMNAMAPKAPK2 | |
| SCHEMBL16668061 | 0.70 | MAP3K12 (0.36) | TLR7 | |
| SCHEMBL28043957 | 0.69 | NOS2 (0.44) | KMT2ATLR7LMNA | |
| SCHEMBL29586569 | 0.67 | NOS2 (0.42) | HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022208382-A1 | NOVEL DIALKOXYNAPHTHO[2,3-C]FURAN-1(3H)-ONE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING RESPIRATORY DISEASE OR SARS-COV-2 INFECTION DISEASE, COMPRISING SAME | 동화약품주식회사 | 2022-10-06 | — | — | WO | disclosed |