Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23647453 | 1.00 | ADRB1 (0.40) | ADRB1OPRM1GRIN1GRIN2ASIGMAR1 | |
| SCHEMBL1604324 | 0.86 | HDAC4 (0.43) | OPRM1GRIN1GRIN2AHDAC4GRIN2D | |
| SCHEMBL30344664 | 0.86 | HDAC4 (0.43) | OPRM1GRIN1GRIN2AHDAC4GRIN2D | |
| Hydrochloric Acid SCHEMBL2364251 | 0.84 | HDAC4 (0.42) | GRIN1GRIN2AHDAC4GRIN2DGRIN3B | |
| SCHEMBL18742758 | 0.82 | HDAC4 (0.44) | GRIN1GRIN2AHDAC4GRIN2DGRIN3B | |
| SCHEMBL8284917 | 0.82 | HDAC4 (0.49) | GRIN1GRIN2AHDAC4GRIN2DGRIN3B | |
| SCHEMBL29857957 | 0.82 | HDAC4 (0.44) | GRIN1GRIN2AHDAC4GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL18742446 | 0.80 | HDAC4 (0.43) | GRIN1GRIN2AHDAC4GRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL29858001 | 0.80 | HDAC4 (0.43) | GRIN1GRIN2AHDAC4GRIN2DGRIN3B | |
| SCHEMBL652087 | 0.77 | SIGMAR1 (0.57) | ADRB1OPRM1GRIN1GRIN2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867720-B | Heteroaryl derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-10-22 | — | — | CN | disclosed |
| US-20230348467-A1 | Heteroaryl Derivative, Preparation Method Therefor, And Use Thereof | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-02 | — | — | US | disclosed |
| EP-4092019-A1 | HETEROARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2022-11-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348467-A1 | Heteroaryl Derivative, Preparation Method Therefor, And Use Thereof | PTPN11, PTPN1, PTPN7 | ADRB1 1622/4885OPRM1 4509/4885GRIN1 2023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.