Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 5/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KYNU | Q16719 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880162 | 1.00 | GAA (0.42) | GAACA12CA1CA2CYP2C9 | |
| Carbamic Acid SCHEMBL28340527 | 0.92 | KYNU (0.42) | GAACA12CA1CA2CYP2C9 | |
| SCHEMBL20226656 | 0.82 | GAA (0.39) | GAACA12CA1CA2CA4 | |
| SCHEMBL776476 | 0.80 | PTGES2 (0.44) | PSIP1ALOX5APFEN1KMT2AHSD17B10 | |
| SCHEMBL30018950 | 0.80 | GAA (0.45) | GAACA12CA1CA2CYP2C9 | |
| SCHEMBL12325100 | 0.80 | GAA (0.45) | GAACA12CA1CA2CYP2C9 | |
| SCHEMBL1972988 | 0.79 | GAA (0.60) | GAACA12CA1CA2CYP2C9 | |
| Hydrochloric Acid SCHEMBL20399177 | 0.78 | GAA (0.43) | GAACA12CA1CA2CYP2C9 | |
| SCHEMBL23364695 | 0.78 | CA2 (0.61) | GAACA12CA1CA2CYP2C9 | |
| SCHEMBL11406615 | 0.77 | GAA (0.42) | GAACA12CA1CA2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115925693-B | JAK1 selective inhibitors | 阿斯利康(瑞典)有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-115925693-A | Selective inhibitors of JAK1 | 阿斯利康(瑞典)有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-110461830-B | Selective inhibitors of JAK1 | 阿斯利康(瑞典)有限公司 | 2022-11-01 | — | — | CN | disclosed |