SCHEMBL30019633

SCHEMBL30019633

CC(C)C[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ KDM1A O60341 3/20 0.45
▸ REN P00797 8/20 0.44
▸ MAPK8 P45983 1/20 0.44
▸ MAPK9 P45984 1/20 0.44
▸ MAPK10 P53779 1/20 0.44
▸ NMUR2 Q9GZQ4 3/20 0.44
▸ MAOB P27338 1/20 0.41
▸ KDM5A P29375 1/20 0.41
▸ KDM1B Q8NB78 1/20 0.41
▸ TACR1 P25103 1/20 0.41
▸ NMUR1 Q9HB89 2/20 0.40
▸ KEAP1 Q14145 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30198552 0.91 KDM1A (0.46) KDM1ARENMAPK8MAPK9MAPK10
SCHEMBL29977789 0.89 MAPK8 (0.46) KDM1ARENMAPK8MAPK9MAPK10
SCHEMBL30199670 0.89 MAPK8 (0.46) KDM1ARENMAPK8MAPK9MAPK10
SCHEMBL30400982 0.88 MAPK8 (0.48) KDM1ARENMAPK8MAPK9MAPK10
SCHEMBL30198364 0.88 KDM1A (0.48) KDM1ARENMAPK8MAPK9MAPK10
SCHEMBL30930555 0.86 CXCL8 (0.49) KDM1ARENMAPK8MAPK9MAPK10
SCHEMBL30355011 0.85 NMUR2 (0.45) NMUR2NMUR1
SCHEMBL29390800 0.85 NMUR2 (0.45) NMUR2NMUR1
SCHEMBL30400976 0.85 NMUR2 (0.45) NMUR2NMUR1
SCHEMBL30311227 0.84 MAPK8 (0.45) KDM1ARENMAPK8MAPK9MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111032850-B Oligomeric particle reagents and methods of use thereof 朱诺治疗学有限公司 2024-08-13 — — CN disclosed
CN-117106716-A Method for culturing cells and kit and device for use in the method 朱诺治疗学有限公司 2023-11-24 — — CN disclosed
CN-116875635-A Method, reagent cartridge, reagent and device for transduction 朱诺治疗学有限公司 2023-10-13 — — CN disclosed
CN-116656605-A Methods, kits and devices for expanding cell populations 朱诺治疗有限公司 2023-08-29 — — CN disclosed
CN-108474002-B Method, reagent cartridge, reagent and device for transduction 朱诺治疗学有限公司 2023-05-23 — — CN disclosed
CN-108431210-B Method for culturing cells and kit and device for use in the method 朱诺治疗学有限公司 2023-05-23 — — CN disclosed
CN-115261317-A Method for culturing cells, and kit and apparatus for the same 朱诺治疗学有限公司 2022-11-01 — — CN disclosed
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