SCHEMBL30021759

SCHEMBL30021759

O=C1CC=CC=C1c1ccccc1.[Ir+3]

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 3/20 0.38
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
CFTR P13569 1/20 0.34
GOPC Q9HD26 1/20 0.34
SIGMAR1 Q99720 3/20 0.33
PTPN1 P18031 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PTPRC P08575 1/20 0.33
PTPRF P10586 1/20 0.33
CDC25B P30305 1/20 0.33
HSD17B3 P37058 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
DRD2 P14416 1/20 0.33
PDE4B Q07343 2/20 0.33
AXL P30530 1/20 0.32
APP P05067 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668518 0.98 BACE1 (0.39) BACE1MAOAMAOBCFTRGOPC
SCHEMBL6272816 0.94 HSD17B3 (0.40) BACE1MAOAMAOBCFTRGOPC
Thianthrene SCHEMBL31297765 0.88 BACE1 (0.36) BACE1MAOAMAOBSIGMAR1SMN1; SMN2
SCHEMBL30648241 0.85 KMO (0.42) MAOASMN1; SMN2LMNAMAPTHTT
SCHEMBL29362581 0.83 PTPN1 (0.38) BACE1PTPN1SMN1; SMN2PTPRCPTPRF
SCHEMBL28610811 0.83 PTPN1 (0.38) BACE1PTPN1SMN1; SMN2PTPRCPTPRF
SCHEMBL30381926 0.82 PTPN1 (0.37) BACE1PTPN1SMN1; SMN2PTPRCPTPRF
SCHEMBL11666200 0.81
SCHEMBL9764763 0.78 ESR1 (0.37) BACE1PTPN1
SCHEMBL5848037 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022244864-A1 MIXED POWDER, VAPOR DEPOSITION METHOD FOR ORGANIC COMPOUND, METHOD FOR PRODUCING ORGANIC ELECTROLUMINESCENT ELEMENT, METHOD FOR SELECTING ORGANIC COMPOUND, AND VAPOR DEPOSITION METHOD 出光興産株式会社 2022-11-24 WO disclosed