Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.36 |
| ▸ | BACE1 | P56817 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272816 | 0.81 | HSD17B3 (0.40) | BACE1PTPN1 | |
| SCHEMBL6941812 | 0.80 | APP (0.43) | — | |
| SCHEMBL668518 | 0.80 | BACE1 (0.39) | BACE1PTPN1 | |
| SCHEMBL30021759 | 0.78 | BACE1 (0.38) | BACE1PTPN1 | |
| SCHEMBL10589880 | 0.77 | KIF11 (0.38) | GAAMMP3 | |
| SCHEMBL5848037 | 0.76 | — | — | |
| SCHEMBL13519167 | 0.74 | CA1 (0.45) | — | |
| SCHEMBL29504872 | 0.72 | SENP1 (0.52) | ESR1ESR2MGAMGAASI | |
| SCHEMBL27642713 | 0.71 | ESR2 (0.43) | ESR1ESR2SENP1HSD17B1MMP3 | |
| SCHEMBL11869896 | 0.71 | ESR1 (0.39) | ESR1ESR2MGAMGAASI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0428720-A1 | OPTICALLY ACTIVE COMPOUNDS AND LIQUID CRYSTAL PHASE. | MERCK PATENT GMBH (DE) | 1991-05-29 | — | — | EP | disclosed |