SCHEMBL30021779

SCHEMBL30021779

c1ccc(-c2cccc(N(c3ccccc3)c3ccccc3)c2N(c2ccccc2)c2c(-c3ccccc3)cccc2N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
HSD17B10 Q99714 2/20 0.35
HPGD P15428 1/20 0.35
BCL2L1 Q07817 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAPK1 P28482 1/20 0.35
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
MAPT P10636 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KCNA3 P22001 1/20 0.33
PDCD1 Q15116 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
HNF4A P41235 1/20 0.32
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3824743 0.96 ALDH1A1 (0.35) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL5419249 0.92 ALDH1A1 (0.41) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Diphenylamine SCHEMBL28068924 0.86 HSD17B10 (0.39) ALDH1A1HSD17B10HPGDMAPK1KDM4E
SCHEMBL28002432 0.86 ALDH1A1 (0.39) ALDH1A1MAPK1KDM4ECYP1A2CYP3A4
SCHEMBL1900260 0.86 HTR7 (0.38) ALDH1A1MAPK1KDM4ECYP1A2CYP3A4
SCHEMBL29127434 0.86 KDM1A (0.39) ALDH1A1HSD17B10HPGDMAPK1CYP1A2
SCHEMBL30332550 0.85 ALDH1A1 (0.33) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL8366035 0.84 HTR7 (0.38) ALDH1A1HPGDMAPK1CYP2C19TDP1
SCHEMBL1551517 0.84 ALDH1A1 (0.40) ALDH1A1HSD17B10HPGDBCL2L1CYP3A4
SCHEMBL3877945 0.84 HTR7 (0.39) ALDH1A1HPGDMAPTL3MBTL1PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022244864-A1 MIXED POWDER, VAPOR DEPOSITION METHOD FOR ORGANIC COMPOUND, METHOD FOR PRODUCING ORGANIC ELECTROLUMINESCENT ELEMENT, METHOD FOR SELECTING ORGANIC COMPOUND, AND VAPOR DEPOSITION METHOD 出光興産株式会社 2022-11-24 WO disclosed