SCHEMBL30022895

SCHEMBL30022895

CC(C)(C)OC(=O)N[C@H]1CCCN(c2ncc(C(N)=O)c(Nc3cc(-c4ccccc4)c4c(c3)C(C)(C)C(=O)N4)n2)C1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CAMK1D Q8IU85 19/20 0.76
▸ BTK Q06187 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23113398 0.91 CAMK1D (0.83) CAMK1D
SCHEMBL23113396 0.91 CAMK1D (0.83) CAMK1D
SCHEMBL30022237 0.89 CAMK1D (0.74) CAMK1DBTK
SCHEMBL30020772 0.88 CAMK1D (0.77) CAMK1DBTK
SCHEMBL30022441 0.88 CAMK1D (0.75) CAMK1D
SCHEMBL30022889 0.87 CAMK1D (0.75) CAMK1DBTK
SCHEMBL30020760 0.87 CAMK1D (0.74) CAMK1DBTK
SCHEMBL23113312 0.86 CAMK1D (1.00) CAMK1D
SCHEMBL23113330 0.86 CAMK1D (1.00) CAMK1D
SCHEMBL30022863 0.86 CAMK1D (0.55) CAMK1DBTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11530193-B2 Kinase inhibitors THE UNIVERSITY OF MANCHESTER (GB) 2022-12-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11530193-B2 Kinase inhibitors CAMKK2, CAMK1, CAMKK1 CAMK1D 5/4885BTK 1532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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