Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | SELL | P14151 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656665 | 0.85 | HDAC1 (0.73) | KDM4EMAPTHSD17B10ALOX15ALDH1A1 | |
| SCHEMBL8102700 | 0.81 | MAPT (0.57) | KDM4EMAPTHSD17B10ALOX15ALDH1A1 | |
| SCHEMBL5698189 | 0.80 | HDAC1 (0.61) | KDM4EMAPTHSD17B10ALOX15ALDH1A1 | |
| SCHEMBL30023407 | 0.80 | HDAC1 (0.61) | KDM4EMAPTHSD17B10ALOX15ALDH1A1 | |
| SCHEMBL93340 | 0.80 | HDAC1 (0.66) | KDM4EMAPTHSD17B10ALOX15ALDH1A1 | |
| SCHEMBL29366288 | 0.80 | HDAC1 (0.66) | KDM4EMAPTHSD17B10ALOX15ALDH1A1 | |
| SCHEMBL30152439 | 0.79 | KDM4E (0.56) | KDM4EMAPTHSD17B10ALOX15ALDH1A1 | |
| SCHEMBL5710374 | 0.78 | MEN1 (0.62) | KDM4EMAPTALDH1A1HPGDCNR1 | |
| SCHEMBL30374720 | 0.78 | MEN1 (0.62) | KDM4EMAPTALDH1A1HPGDCNR1 | |
| SCHEMBL11858542 | 0.77 | LIG1 (0.65) | KDM4EHSD17B10ALOX15ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115490585-A | Polyhydroxy-substituted benzophenone derivative and application thereof in preventing iron death of liver cells | 山西医科大学 | 2022-12-20 | — | — | CN | disclosed |