Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 15/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19569213 | 1.00 | ATF4 (0.48) | ATF4RAB9AGRM5LMNATSHR | |
| SCHEMBL30025068 | 0.92 | ATF4 (0.57) | ATF4 | |
| SCHEMBL20974263 | 0.92 | ATF4 (0.57) | ATF4 | |
| SCHEMBL22669133 | 0.85 | RAB9A (0.41) | RAB9AGRM5LMNATSHR | |
| SCHEMBL22669479 | 0.84 | ATF4 (0.48) | ATF4RAB9A | |
| SCHEMBL19569469 | 0.82 | ATF4 (0.50) | ATF4 | |
| SCHEMBL30025703 | 0.82 | ATF4 (0.50) | ATF4 | |
| SCHEMBL19569461 | 0.81 | ATF4 (0.53) | ATF4 | |
| SCHEMBL30025585 | 0.81 | ATF4 (0.53) | ATF4 | |
| SCHEMBL22668959 | 0.81 | ATF4 (0.71) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115947681-A | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-109641844-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2022-11-01 | — | — | CN | disclosed |