SCHEMBL30025316

SCHEMBL30025316

Cc1ccc(OCC(=O)NC23CC(NC(=O)COc4ccc(Cl)c(F)c4)(C2)C3)c(N)n1

nearest known ligand 0.59

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ATF4 P18848 20/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19569221 1.00 ATF4 (0.59) ATF4
SCHEMBL20999313 0.93 ATF4 (0.49) ATF4
SCHEMBL19569432 0.90 ATF4 (0.61) ATF4
SCHEMBL19555312 0.90 ATF4 (0.61) ATF4
SCHEMBL19569426 0.90 ATF4 (0.61) ATF4
SCHEMBL30025819 0.90 ATF4 (0.61) ATF4
SCHEMBL20974048 0.90 ATF4 (0.61) ATF4
SCHEMBL30025683 0.90 ATF4 (0.61) ATF4
SCHEMBL19569599 0.89 ATF4 (0.59) ATF4
SCHEMBL30025762 0.89 ATF4 (0.59) ATF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115947681-A Modulators of integrated stress pathways 卡里科生命科学有限责任公司 2023-04-11 — — CN disclosed
CN-109641844-B Modulators of integrated stress pathways 卡里科生命科学有限责任公司 2022-11-01 — — CN disclosed
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