Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 7/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 7/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 12/20 | 0.39 |
| ▸ | PRKDC | P78527 | 12/20 | 0.39 |
| ▸ | MTOR | P42345 | 7/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23540563 | 1.00 | DDB1 (0.58) | DDB1CRBNPIK3CAPRKDCMTOR | |
| SCHEMBL23541310 | 0.89 | CRBN (0.63) | DDB1CRBN | |
| SCHEMBL30026841 | 0.89 | DDB1 (0.53) | DDB1CRBNPIK3CAPRKDCMTOR | |
| SCHEMBL23540937 | 0.89 | DDB1 (0.53) | DDB1CRBNPIK3CAPRKDCMTOR | |
| SCHEMBL25036606 | 0.85 | CRBN (0.58) | DDB1CRBNPIK3CAPRKDCMTOR | |
| SCHEMBL23842108 | 0.84 | DDB1 (0.72) | DDB1CRBN | |
| SCHEMBL23541139 | 0.81 | DDB1 (0.64) | DDB1CRBN | |
| SCHEMBL24818103 | 0.81 | CRBN (0.70) | DDB1CRBN | |
| SCHEMBL23541240 | 0.79 | CRBN (0.58) | DDB1CRBNPIK3CAPRKDC | |
| SCHEMBL31304855 | 0.79 | CRBN (0.58) | DDB1CRBNPIK3CAPRKDCMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4077319-A1 | PROTEIN TYROSINE PHOSPHATASE DEGRADERS AND METHODS OF USE THEREOF | Calico Life Sciences LLC (US) | 2022-10-26 | — | — | EP | disclosed |