Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24959005 | 1.00 | HTR7 (0.43) | HTR7RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL30029312 | 0.82 | HTR7 (0.47) | HTR7RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL24958809 | 0.82 | HTR7 (0.47) | HTR7RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL24959192 | 0.80 | HTR7 (0.44) | HTR7RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL30027652 | 0.80 | HTR7 (0.44) | HTR7RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL24958950 | 0.79 | TRPM5 (0.45) | HTR7KDM4E | |
| SCHEMBL30029030 | 0.79 | TRPM5 (0.45) | HTR7KDM4E | |
| SCHEMBL24960044 | 0.79 | HTR7 (0.40) | HTR7RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL31438106 | 0.79 | HTR7 (0.43) | HTR7RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL24959231 | 0.79 | HTR7 (0.40) | HTR7RAB9ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4271674-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022225914-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-10-27 | — | — | WO | disclosed |