SCHEMBL300287

SCHEMBL300287

O=C(O)[C@H](CO)Nc1ccc(O)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERCC1 P07992 1/20 0.46
ERCC4 Q92889 1/20 0.46
CA2 P00918 7/20 0.41
CA1 P00915 6/20 0.41
KDM6B O15054 1/20 0.41
CA12 O43570 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40
KDM4E B2RXH2 8/20 0.40
HSD17B10 Q99714 5/20 0.40
TDP1 Q9NUW8 5/20 0.40
HIF1A Q16665 4/20 0.40
RECQL P46063 2/20 0.40
PTGS2 P35354 2/20 0.40
USP2 O75604 1/20 0.40
EGFR P00533 1/20 0.40
LCK P06239 1/20 0.40
FYN P06241 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300286 1.00 ERCC1 (0.46) ERCC1ERCC4CA2CA1KDM6B
Hydrochloric Acid SCHEMBL15266596 0.98 ERCC1 (0.45) ERCC1ERCC4CA2CA1KDM6B
SCHEMBL2283372 0.85 GAA (0.42) ERCC1ERCC4CA2CA1KDM6B
SCHEMBL4159980 0.82 TSHR (0.49) CA2CA1CA12CA9CA14
SCHEMBL4159978 0.82 TSHR (0.49) CA2CA1CA12CA9CA14
SCHEMBL29051409 0.81 PPARG (0.50) ERCC1ERCC4CA2CA1NPSR1
SCHEMBL30467554 0.81 PPARG (0.50) ERCC1ERCC4CA2CA1NPSR1
SCHEMBL18144294 0.80 CA2 (0.44) CA2CA1CA12CA9CA14
SCHEMBL1794244 0.80 CA2 (0.44) CA2CA1CA12CA9CA14
SCHEMBL31540140 0.80 CA2 (0.47) ERCC1ERCC4CA2CA1KDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116478225-B Preparation method and application of serine modified cordycepin phosphate drug molecule 南京工业大学 2024-06-11 CN claimed
CN-117750978-A Synthetic peptide shuttle bioconjugates for intracellular cargo delivery 费尔丹生物公司 2024-03-22 CN claimed
CN-117305198-A Recombinant bacterium and application thereof in synthesis of L-3, 4-dihydroxyphenylalanine 杭州唯铂莱生物科技有限公司 2023-12-29 CN claimed
CN-116615227-A Minimum length shuttle peptide suitable for transduction of Cas9-RNP and other nucleoprotein loads and variants thereof 费尔丹生物公司 2023-08-18 CN claimed
CN-116478225-A Preparation method and application of serine modified cordycepin phosphate drug molecule 南京工业大学 2023-07-25 CN claimed
EP-2709608-B1 COMPOSITIONS FOR TREATING POSTURAL REFLEX ABNORMALITY CAUSED BY PARKINSON'S DISEASE LUNDBECK NA LTD (US) 2016-08-10 EP claimed
US-9364453-B2 Method of treating postural reflex abnormality caused by parkinson's disease LUNDBECK NA LTD. (US) 2016-06-14 US claimed
WO-2015127558-A1 METHODS AND USES FOR INDUCING OR FACILITATING MICTURITION IN A PATIENT IN NEED THEREOF UNIVERSITé LAVAL (CA) 2015-09-03 WO claimed
US-20140378546-A1 METHOD OF TREATING POSTURAL REFLEX ABNORMALITY CAUSED BY PARKINSON'S DISEASE Chelsea Therapeutics, Inc (US) 2014-12-25 US claimed
EP-2709608-A1 METHOD OF TREATING POSTURAL REFLEX ABNORMALITY CAUSED BY PARKINSON'S DISEASE Chelsea Therapeutics Inc. (US) 2014-03-26 EP claimed
EP-0742494-A1 Novolak containing photoresist stripper composition OCG MICROELECTRONIC MATERIALS, INC. (US) 1996-11-13 EP claimed
US-5561105-A MIXTURE OF SOLVENT, AMINE AND CHELATE COMPOUND OCG MICROELECTRONIC MATERIALS, INC. (US) 1996-10-01 US claimed
US-5507978-A CORROSION RESISTANCE OCG MICROELECTRONIC MATERIALS, INC. (US) 1996-04-16 US claimed
US-5472830-A Mixture of polar organic solvent, amine and hydroxy amino acid OCG MICROELECTRONIC MATERIALS, INC. (US) 1995-12-05 US claimed
EP-0678788-A2 Non-corrosive photoresist stripping composition OCG MICROELECTRONIC MATERIALS, INC. (US) 1995-10-25 EP claimed
EP-0580409-A2 Cosmetic composition containing DOPA derivatives UNILEVER PLC (GB) 1994-01-26 EP claimed
US-4690949-A ADMINISTERING 3,4-DIHYDROXYPHENYLSERINE SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1987-09-01 US claimed
US-4529603-A Erythro-3,4-dihydroxyphenylserine SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-07-16 US claimed
US-4497826-A THREO-3,4-DIHYDROXYPHENYLSERINE, CARBIDOPA AND BENSERAZIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1985-02-05 US claimed
US-4330558-A 3,4-DIHYDROXYPHENYLSERINE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-05-18 US claimed