SCHEMBL30030991

SCHEMBL30030991

C[C@@H]1CC[C@H](CNC(=O)OC(C)(C)C)c2ncccc21

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ACACB O00763 8/20 0.45
▸ ACACA Q13085 5/20 0.45
▸ FNTA P49354 1/20 0.41
▸ FNTB P49356 1/20 0.41
▸ CKS1B P61024 1/20 0.40
▸ SKP1 P63208 1/20 0.40
▸ SKP2 Q13309 1/20 0.40
▸ DRD2 P14416 2/20 0.39
▸ PBK Q96KB5 1/20 0.38
▸ METAP1 P53582 1/20 0.38
▸ NAMPT P43490 1/20 0.38
▸ KDM4E B2RXH2 2/20 0.37
▸ PKM P14618 1/20 0.37
▸ PCSK9 Q8NBP7 1/20 0.36
▸ L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30030494 1.00 ACACB (0.45) ACACBACACAFNTAFNTBCKS1B
SCHEMBL27094493 0.83 P2RX7 (0.39) —
SCHEMBL27094573 0.83 P2RX7 (0.39) —
SCHEMBL30031899 0.80 ACACB (0.43) ACACBACACAFNTAFNTBCKS1B
SCHEMBL30031343 0.79 ACACB (0.45) ACACBACACAFNTAFNTBCKS1B
SCHEMBL30030597 0.76 ACACB (0.40) ACACBACACAFNTAFNTBCKS1B
SCHEMBL30030896 0.76 ACACB (0.40) ACACBACACAFNTAFNTBCKS1B
SCHEMBL30030986 0.76 ACACB (0.40) ACACBACACAFNTAFNTBCKS1B
SCHEMBL30030516 0.74 ACACB (0.44) ACACBACACAFNTAFNTBCKS1B
SCHEMBL29142419 0.74 ACACB (0.44) ACACBACACAFNTAFNTBCKS1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035379-A1 BICYCLIC PYRIDINE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2026-02-05 — — US disclosed
US-12534475-B2 Bicyclic pyridine derivative Sumitomo Pharma Co., Ltd. (JP) 2026-01-27 — — US disclosed
US-12077546-B2 Bicyclic pyridine derivative Sumitomo Pharma Co., Ltd. (JP) 2024-09-03 — — US disclosed
US-20240228505-A1 BICYCLIC PYRIDINE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2024-07-11 — — US disclosed
US-20240150370-A1 BICYCLIC PYRIDINE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2024-05-09 — — US disclosed
EP-4324834-A1 BICYCLIC PYRIDINE DERIVATIVE Sumitomo Pharma Co., Ltd. (JP) 2024-02-21 — — EP disclosed
WO-2022215754-A1 BICYCLIC PYRIDINE DERIVATIVE 住友ファーマ株式会社 2022-10-13 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035379-A1 BICYCLIC PYRIDINE DERIVATIVE CBR1, CBR3, CYP2B6 ACACB 2159/4885ACACA 2405/4885FNTA 4515/4885
US-20240228505-A1 BICYCLIC PYRIDINE DERIVATIVE CBR1, CBR3, CYB5R3 ACACB 3045/4885ACACA 3529/4885FNTA 4791/4885
US-12077546-B2 Bicyclic pyridine derivative CBR1, CBR3, CYB5R3 ACACB 3045/4885ACACA 3529/4885FNTA 4791/4885
US-20240150370-A1 BICYCLIC PYRIDINE DERIVATIVE CBR1, CBR3, CYB5R3 ACACB 3045/4885ACACA 3529/4885FNTA 4791/4885
US-12534475-B2 Bicyclic pyridine derivative CBR1, CYP2B6, CBR3 ACACB 1948/4885ACACA 2220/4885FNTA 4441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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