Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.52 |
| ▸ | KDR | P35968 | 11/20 | 0.46 |
| ▸ | RET | P07949 | 2/20 | 0.46 |
| ▸ | KIF5B | P33176 | 2/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 9/20 | 0.46 |
| ▸ | FLT1 | P17948 | 9/20 | 0.46 |
| ▸ | FLT4 | P35916 | 8/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | TEK | Q02763 | 2/20 | 0.46 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.46 |
| ▸ | PLK4 | O00444 | 1/20 | 0.46 |
| ▸ | CIT | O14578 | 1/20 | 0.46 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | STK10 | O94804 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27145045 | 0.87 | EGFR (0.57) | EGFRKDREPHA2ALK | |
| SCHEMBL30822070 | 0.86 | EGFR (0.53) | EGFRKDRRETKIF5BFGFR1 | |
| SCHEMBL27136300 | 0.85 | EGFR (0.73) | EGFRRETRIPK2ERBB2MET | |
| SCHEMBL30820513 | 0.85 | EGFR (0.73) | EGFRRETRIPK2ERBB2MET | |
| SCHEMBL30032029 | 0.84 | EGFR (0.58) | EGFRKDRRETKIF5BFGFR1 | |
| SCHEMBL30030964 | 0.80 | EGFR (0.52) | EGFRKDRRETKIF5BFGFR1 | |
| SCHEMBL29168707 | 0.77 | EGFR (0.61) | EGFRKDRRETKIF5BFGFR1 | |
| SCHEMBL30820387 | 0.77 | EGFR (0.61) | EGFRKDRRETKIF5BFGFR1 | |
| SCHEMBL27145372 | 0.74 | EGFR (0.57) | EGFRKDRERBB2EPHA2 | |
| SCHEMBL30822108 | 0.73 | EGFR (0.57) | EGFRKDRRETKIF5BFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022225238-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | 보로노이 주식회사 | 2022-10-27 | — | — | WO | disclosed |