Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 7/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26974528 | 1.00 | MPO (0.45) | MPOMAOBIDO1CNR1KMT2A | |
| SCHEMBL26971267 | 0.84 | MGMT (0.44) | MPOMAOBIDO1CNR1KMT2A | |
| SCHEMBL30030825 | 0.84 | MGMT (0.44) | MPOMAOBIDO1CNR1KMT2A | |
| SCHEMBL26971158 | 0.83 | MAOB (0.41) | MAOBIDO1CNR1 | |
| SCHEMBL30031439 | 0.83 | MAOB (0.41) | MAOBIDO1CNR1 | |
| SCHEMBL26639213 | 0.83 | MAOB (0.41) | MAOBIDO1CNR1 | |
| SCHEMBL26971268 | 0.82 | MAOB (0.42) | MPOMAOBCNR1KMT2A | |
| SCHEMBL23286976 | 0.82 | IDO1 (0.51) | IDO1 | |
| SCHEMBL29737964 | 0.82 | IDO1 (0.51) | IDO1 | |
| SCHEMBL29687741 | 0.81 | L3MBTL1 (0.45) | MPOMAOBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4271672-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2023-11-08 | — | — | EP | disclosed |
| WO-2022225941-A1 | CARBOXY-BENZIMIDAZOLE GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2022-10-27 | — | — | WO | disclosed |