Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 6/20 | 0.33 |
| ▸ | JUN | P05412 | 4/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.32 |
| ▸ | RELA | Q04206 | 4/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27088164 | 1.00 | USP1 (0.33) | USP1JUNNFKB1NFKB2RELA | |
| SCHEMBL30034048 | 0.84 | USP1 (0.36) | USP1 | |
| SCHEMBL27088240 | 0.84 | USP1 (0.36) | USP1 | |
| SCHEMBL29296024 | 0.80 | USP1 (0.52) | USP1 | |
| SCHEMBL30782773 | 0.80 | USP1 (0.52) | USP1 | |
| SCHEMBL29296052 | 0.80 | USP1 (0.40) | USP1 | |
| SCHEMBL29296058 | 0.79 | USP1 (0.41) | USP1 | |
| SCHEMBL29296065 | 0.78 | USP1 (0.34) | USP1 | |
| SCHEMBL30693863 | 0.78 | USP1 (0.45) | USP1 | |
| SCHEMBL27088186 | 0.78 | USP1 (0.45) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214053-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR | 海南耀臻生物医药科技有限公司 | 2022-10-13 | — | — | WO | disclosed |