Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30032351 | 0.98 | AADAT (0.34) | AADATALDH1A1TSHRTACR1KMT2A | |
| SCHEMBL30031819 | 0.98 | AADAT (0.34) | AADATALDH1A1TSHRTACR1KMT2A | |
| SCHEMBL30031821 | 0.98 | AADAT (0.34) | AADATALDH1A1TSHRTACR1KMT2A | |
| SCHEMBL30031425 | 0.98 | AADAT (0.34) | AADATALDH1A1TSHRTACR1KMT2A | |
| SCHEMBL30031257 | 0.95 | TACR1 (0.34) | AADATALDH1A1TSHRTACR1KMT2A | |
| SCHEMBL30031916 | 0.94 | AADAT (0.33) | AADATTACR1KMT2AMEN1MAPT | |
| SCHEMBL30032122 | 0.92 | AADAT (0.33) | AADATTACR1KMT2AMEN1MAPT | |
| SCHEMBL30031487 | 0.92 | AADAT (0.33) | AADATTACR1KMT2AMEN1MAPT | |
| SCHEMBL30032226 | 0.92 | AADAT (0.33) | AADATTACR1KMT2AMEN1MAPT | |
| SCHEMBL30032607 | 0.92 | ALDH1A1 (0.37) | AADATALDH1A1TSHRKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214937-A1 | SUBSTITUTED TETRACYCLIC CARBOXYLIC ACIDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2022-10-13 | — | — | WO | disclosed |