Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1144576 | 0.85 | KMT2A (0.43) | PARP1KMT2AMEN1PNPACACB | |
| SCHEMBL31337233 | 0.83 | NPC1 (0.41) | KMT2AMEN1PNPACACBHSD11B1 | |
| SCHEMBL31337199 | 0.81 | KMT2A (0.43) | KMT2AMEN1ACACBHSD11B1RAB9A | |
| SCHEMBL30962498 | 0.81 | RAB9A (0.42) | PARP1KMT2AMEN1ACACBHSD11B1 | |
| SCHEMBL12653332 | 0.81 | KMT2A (0.37) | PARP1KMT2AMEN1PNPACACB | |
| SCHEMBL19657122 | 0.81 | CECR2 (0.42) | PARP1KMT2AMEN1PNPACACB | |
| SCHEMBL12618972 | 0.81 | KMT2A (0.37) | PARP1KMT2AMEN1PNPACACB | |
| SCHEMBL29209466 | 0.80 | TSHR (0.45) | PARP1SMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL30980915 | 0.76 | PARP1 (0.45) | PARP1PNPARRAB9ANPC1 | |
| SCHEMBL30962610 | 0.74 | HTT (0.40) | KMT2AMEN1ACACBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279370-A | Compounds for targeted degradation of BRD9 | C4医药公司 | 2022-11-01 | — | — | CN | disclosed |