Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 10/20 | 0.51 |
| ▸ | NOS3 | P29474 | 2/20 | 0.48 |
| ▸ | NOS2 | P35228 | 2/20 | 0.48 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PAH | P00439 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754917 | 0.80 | NOS1 (0.54) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL19204413 | 0.70 | NOS1 (0.47) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL14244119 | 0.65 | — | — | |
| SCHEMBL3454164 | 0.65 | NOS1 (0.53) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL21068021 | 0.65 | NOS1 (1.00) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL31635848 | 0.65 | NOS1 (1.00) | NOS1NOS3NOS2CASP7HSD17B10 | |
| SCHEMBL11151731 | 0.62 | NPY5R (0.36) | KDM4EALDH1A1 | |
| SCHEMBL10805002 | 0.62 | NPY5R (0.36) | KDM4EALDH1A1 | |
| SCHEMBL10805007 | 0.62 | NPY5R (0.36) | KDM4EALDH1A1 | |
| SCHEMBL15757443 | 0.62 | UHRF1 (0.42) | NOS1NOS3NOS2CASP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022214053-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR | 海南耀臻生物医药科技有限公司 | 2022-10-13 | — | — | WO | disclosed |