Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23796757 | 1.00 | KMT2A (0.49) | KMT2APKMCYP1A2ALDH1A1AKR1C3 | |
| SCHEMBL30030693 | 0.89 | AKR1C3 (0.58) | KMT2APKMALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL30032280 | 0.89 | PKM (0.63) | KMT2APKMCYP1A2ALDH1A1AKR1C3 | |
| SCHEMBL23796486 | 0.89 | AKR1C3 (0.58) | KMT2APKMALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL23796739 | 0.89 | PKM (0.63) | KMT2APKMCYP1A2ALDH1A1AKR1C3 | |
| SCHEMBL23796590 | 0.87 | PKM (0.65) | KMT2APKMCYP1A2ALDH1A1AKR1C3 | |
| SCHEMBL30031873 | 0.87 | PKM (0.65) | KMT2APKMCYP1A2ALDH1A1AKR1C3 | |
| SCHEMBL23796382 | 0.87 | AKR1C3 (0.59) | KMT2APKMALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL30031163 | 0.87 | AKR1C3 (0.59) | KMT2APKMALDH1A1AKR1C3AKR1C2 | |
| SCHEMBL23796747 | 0.84 | ALDH1A1 (0.44) | KMT2APKMCYP1A2ALDH1A1AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4118069-B1 | PARA-HYDROQUINONE DERIVATIVES AS VEGF, TNF AND/OR IL INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATORY DISEASES | OM PHARMA SA (CH) | 2024-10-23 | — | — | EP | claimed |
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | claimed |
| CN-115279730-A | 2, 5-or 2, 6-disubstituted hydroquinone derivatives having at least one carboxyl, sulfo or amido group useful as medicaments | OM药物公司 | 2022-11-01 | — | — | CN | disclosed |