Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | DDR1 | Q08345 | 13/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30033508 | 0.89 | HSP90AA1 (0.43) | HSP90AA1DDR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL30032806 | 0.88 | DDR1 (0.43) | HSP90AA1DDR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL30032902 | 0.84 | HSP90AA1 (0.48) | HSP90AA1DDR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL30032738 | 0.78 | HSP90AA1 (0.43) | HSP90AA1DDR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL30033349 | 0.77 | DDR1 (0.44) | HSP90AA1DDR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL30034350 | 0.76 | NPEPPS (0.42) | HSP90AA1DDR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL30033014 | 0.75 | HSP90AA1 (0.43) | HSP90AA1DDR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL30033019 | 0.75 | DDR1 (0.52) | HSP90AA1DDR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL30033004 | 0.73 | NPEPPS (0.49) | HSP90AA1DDR1MEN1CYP1A2CYP3A4 | |
| SCHEMBL30032253 | 0.73 | DDR1 (0.40) | HSP90AA1DDR1MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |