Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.43 |
| ▸ | DDR1 | Q08345 | 9/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30034350 | 0.91 | NPEPPS (0.42) | HSP90AA1KIF11MEN1CYP1A2CYP3A4 | |
| SCHEMBL30032220 | 0.87 | NPEPPS (0.42) | HSP90AA1KIF11NPEPPSDDR1KDM4E | |
| SCHEMBL30033508 | 0.85 | HSP90AA1 (0.43) | HSP90AA1KIF11MEN1CYP1A2CYP3A4 | |
| SCHEMBL30032806 | 0.84 | DDR1 (0.43) | HSP90AA1KIF11MEN1CYP1A2CYP3A4 | |
| SCHEMBL30033338 | 0.84 | HSP90AA1 (0.42) | HSP90AA1KIF11MEN1CYP1A2CYP3A4 | |
| SCHEMBL30032738 | 0.84 | HSP90AA1 (0.43) | HSP90AA1KIF11MEN1CYP1A2CYP3A4 | |
| SCHEMBL30033459 | 0.84 | PKM (0.43) | HSP90AA1KIF11NPEPPSDDR1KDM4E | |
| SCHEMBL30033336 | 0.83 | GRIN1 (0.39) | HSP90AA1 | |
| SCHEMBL31509793 | 0.83 | NPEPPS (0.57) | CYP1A2NPEPPSKDM4EHTTCA12 | |
| SCHEMBL30032168 | 0.83 | NPEPPS (0.49) | MEN1CYP1A2CYP3A4MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |