Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30034563 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL6901730 | 0.83 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL18870328 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL31756582 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL10576442 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL3196831 | 0.75 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL23857484 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL11676672 | 0.74 | ALDH1A1 (0.49) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL15416046 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL5739433 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022224223-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES | NOVARTIS AG (CH) | 2022-10-27 | — | — | WO | disclosed |