Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30032752 | 0.85 | MAPT (0.40) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL30033403 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL3196831 | 0.77 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL23857484 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL11676672 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL30034563 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL15416046 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6901730 | 0.76 | ALDH1A1 (0.47) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL5896904 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6225021 | 0.74 | MAPT (0.44) | ALDH1A1MAPTKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001877-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2026-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001877-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | CNR1, SCN1B, OPRL1 | ALDH1A1 1503/4885MAPT 4460/4885KMT2A 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.