Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 19/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27088259 | 1.00 | USP1 (0.37) | USP1MMP13 | |
| SCHEMBL29878992 | 0.80 | USP1 (0.39) | USP1 | |
| SCHEMBL27031623 | 0.80 | USP1 (0.39) | USP1 | |
| SCHEMBL27088277 | 0.80 | USP1 (0.35) | USP1 | |
| SCHEMBL30032936 | 0.80 | USP1 (0.35) | USP1 | |
| SCHEMBL31368702 | 0.78 | USP1 (0.44) | USP1MMP13 | |
| SCHEMBL27097114 | 0.78 | USP1 (0.37) | USP1 | |
| SCHEMBL29878759 | 0.74 | USP1 (0.39) | USP1 | |
| SCHEMBL27031709 | 0.74 | USP1 (0.39) | USP1 | |
| SCHEMBL25430986 | 0.74 | USP1 (0.38) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117136189-A | Ubiquitin-specific protease 1 (USP 1) inhibitors | 先声再明医药有限公司 | 2023-11-28 | — | — | CN | disclosed |
| WO-2022214053-A1 | UBIQUITIN-SPECIFIC PROTEASE 1 (USP1) INHIBITOR | 海南耀臻生物医药科技有限公司 | 2022-10-13 | — | — | WO | disclosed |