Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23591270 | 1.00 | KDM4E (0.40) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL23578549 | 0.84 | SIRT6 (0.40) | KDM4EALDH1A1MAPTGAAPOLB | |
| SCHEMBL30183710 | 0.84 | SIRT6 (0.40) | KDM4EALDH1A1MAPTGAAPOLB | |
| SCHEMBL23591294 | 0.80 | SMN1; SMN2 (0.44) | KDM4EALDH1A1HSD17B10HPGDGAA | |
| SCHEMBL23577945 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL30184152 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL23577773 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL23578246 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL23591052 | 0.76 | KDM4E (0.44) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL23578377 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1MAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4081521-A1 | SUBSTITUTED TRICYCLIC COMPOUNDS | Lupin Limited (IN) | 2022-11-02 | — | — | EP | disclosed |