SCHEMBL300362

SCHEMBL300362

CC(C)c1cccc(C(C)C)c1N1C(=O)c2cccc3cccc(c23)C1=O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.61
ANPEP P15144 3/20 0.61
NR1H2 P55055 1/20 0.60
NR1H3 Q13133 1/20 0.60
ALDH1A1 P00352 6/20 0.53
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
KDM4E B2RXH2 4/20 0.49
HPGD P15428 3/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CYP1B1 Q16678 1/20 0.49
ERCC1 P07992 1/20 0.49
FEN1 P39748 1/20 0.49
ERCC4 Q92889 1/20 0.49
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17531021 0.88 ANPEP (0.67) DPP4ANPEPNR1H2NR1H3ALDH1A1
SCHEMBL30954668 0.88 ANPEP (0.67) DPP4ANPEPNR1H2NR1H3ALDH1A1
SCHEMBL2820118 0.86 DPP4 (0.78) DPP4ANPEPNR1H2NR1H3KMT2A
SCHEMBL29366407 0.86 DPP4 (0.78) DPP4ANPEPNR1H2NR1H3KMT2A
SCHEMBL1679993 0.85 ANPEP (0.53) DPP4ANPEPNR1H2NR1H3ALDH1A1
SCHEMBL20110421 0.84 DPP4 (0.55) DPP4ANPEPNR1H2NR1H3ALDH1A1
SCHEMBL6925321 0.83 ANPEP (0.66) DPP4ANPEPNR1H2NR1H3MEN1
SCHEMBL13478139 0.82 ANPEP (0.60) DPP4ANPEPNR1H2NR1H3MEN1
SCHEMBL3438530 0.82 ANPEP (0.60) DPP4ANPEPNR1H2NR1H3MEN1
SCHEMBL29369271 0.82 ANPEP (0.60) DPP4ANPEPNR1H2NR1H3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344291-A Method for preparing imide by rearrangement of isoamide and application thereof 中国石油化工股份有限公司 2024-07-16 CN disclosed
CN-106749017-B A kind of synthetic method for 1, the 8- naphthalimide that 3,6 halogen atoms replace 南昌大学 2019-05-24 CN disclosed
CN-106749017-A A kind of synthetic method of 1,8 naphthalimides of 3,6 halogen atoms substitution 南昌大学 2017-05-31 CN disclosed
EP-1501897-B1 METHOD FOR THE PRODUCTION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIIMIDES AND PERYLEN-3,4:9,10-TETRACARBOXYLIC ACID DIANHYDRIDE AND NAPHTALENE-1,8-DICARBOXYLIMIDES BASF SE (DE) 2012-03-14 EP disclosed
US-7807836-B2 Preparation of perylen-3,4:9,10-tetracarboxylic dianhydride and also of naphtalene-1,8-dicarboximides BASF AKTIENGESELLSCHAFT (DE) 2010-10-05 US disclosed
US-20080161569-A1 PREPARATION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC DIANHYDRIDE AND ALSO OF NAPHTALENE-1,8-DICARBOXIMIDES BASF AKTIENGESELLSCHAFT (DE) 2008-07-03 US disclosed
US-7393956-B2 Method for the production of perylen-3,4:9,10-tetracarboxylic acid diimides and perylen-3,4:9,10-tetracarboxylic acid dianhydride and naphtalene-1,8-dicarboxylimides BASF AKTIENGESELLSCHAFT (DE) 2008-07-01 US disclosed
US-7358362-B2 Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis BASF AKTIENGESELLSCHAFT (DE) 2008-04-15 US disclosed
US-20070155968-A1 Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis BASF AKTIENGESELLSCHAFT (DE) 2007-07-05 US disclosed
US-20050131220-A1 Method for the production of perylen-3,4:9,10-tetracarboxylic acid diimides and perylen-3,4:9,10-tetracarboxylic acid dianhydride and naphtalene-1,8-dicarboxylimides BASF AKTIENGESELLSCHAFT (DE) 2005-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161569-A1 PREPARATION OF PERYLEN-3,4:9,10-TETRACARBOXYLIC DIANHYDRIDE AND ALSO OF NAPHTALENE-1,8-DICARBOXIMIDES CLIC1, PNPO, CLIC4 DPP4 4115/4885ANPEP 946/4885NR1H2 1922/4885
US-20070155968-A1 Method for the production of terylene-3,4:11,12-tetracarboxydiimides by direct synthesis HACL2, HRH3, HCN2 DPP4 4569/4885ANPEP 2229/4885NR1H2 1368/4885
US-20050131220-A1 Method for the production of perylen-3,4:9,10-tetracarboxylic acid diimides and perylen-3,4:9,10-tetracarboxylic acid dianhydride and naphtalene-1,8-dicarboxylimides CBR1, CBR3, SCO2 DPP4 4749/4885ANPEP 3435/4885NR1H2 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.