Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.43 |
| ▸ | CTSA | P10619 | 3/20 | 0.42 |
| ▸ | KMO | O15229 | 3/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25552031 | 1.00 | SLC22A12 (0.43) | SLC22A12CTSAKMOEGLN2KDM1A | |
| SCHEMBL25552037 | 0.87 | CTSA (0.44) | SLC22A12CTSAEGLN2KDM1APRKDC | |
| SCHEMBL30037120 | 0.87 | CTSA (0.44) | SLC22A12CTSAEGLN2KDM1APRKDC | |
| SCHEMBL32680061 | 0.83 | DHODH (0.44) | KMOPDK1 | |
| SCHEMBL32680032 | 0.83 | KMO (0.57) | CTSAKMOPDK1 | |
| SCHEMBL25208970 | 0.83 | KMO (0.57) | CTSAKMOPDK1 | |
| SCHEMBL25208397 | 0.83 | DHODH (0.44) | KMOPDK1 | |
| SCHEMBL25552036 | 0.82 | PDK1 (0.41) | SLC22A12CTSAEGLN2KDM1APDK1 | |
| SCHEMBL30037562 | 0.82 | PDK1 (0.41) | SLC22A12CTSAEGLN2KDM1APDK1 | |
| SCHEMBL30036156 | 0.79 | PDK1 (0.45) | SLC22A12KMOEGLN2PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515940-A | Inhibitors of receptor interacting protein kinase I for the treatment of disease | 德州大学系统董事会 | 2022-12-23 | — | — | CN | disclosed |