⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7191437 | 0.70 | — | — | |
| SCHEMBL11850881 | 0.65 | METAP1 (0.31) | — | |
| SCHEMBL3039377 | 0.64 | MAOA (0.45) | — | |
| SCHEMBL746704 | 0.62 | MAOA (0.40) | — | |
| SCHEMBL16238546 | 0.61 | MAOA (0.32) | — | |
| SCHEMBL10544273 | 0.61 | KMT2A (0.36) | — | |
| SCHEMBL890045 | 0.61 | MAOA (0.32) | — | |
| SCHEMBL7997479 | 0.61 | CTH (0.35) | — | |
| SCHEMBL10715549 | 0.61 | MAOA (0.31) | — | |
| SCHEMBL11878757 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8742158-B2 | Protease inhibitors | TaiMed Biologies, Inc. (TW) | 2014-06-03 | — | — | US | disclosed |
| US-20130158261-A1 | PROTEASE INHIBITORS | TAIMED BIOLOGICS, INC. (TW) | 2013-06-20 | — | — | US | disclosed |
| US-8410300-B2 | Protease inhibitors | TAIMED BIOLOGICS, INC. (TW) | 2013-04-02 | — | — | US | disclosed |
| US-20100184974-A1 | Protease Inhibitors | AMBRILIA BIOPHARMA INC. (CA) | 2010-07-22 | — | — | US | disclosed |
| EP-2064177-A2 | PROTEASE INHIBITORS | Ambrilia Biopharma Inc. (CA) | 2009-06-03 | — | — | EP | disclosed |
| WO-2008078200-A2 | PROTEASE INHIBITORS | AMBRILIA BIOPHARMA INC. (CA) | 2008-07-03 | — | — | WO | disclosed |