SCHEMBL300406

SCHEMBL300406

CCOC(=O)NCCCC[Si](OC)(OC)OC

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.47
EPHX1 P07099 1/20 0.47
GLA P06280 1/20 0.46
KMT2A Q03164 1/20 0.46
HDAC3 O15379 1/20 0.41
HDAC4 P56524 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC10 Q969S8 1/20 0.41
HDAC11 Q96DB2 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
HDAC9 Q9UKV0 1/20 0.41
HDAC5 Q9UQL6 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
BRD4 O60885 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5916968 0.98 EPHX1 (0.50) ACHEEPHX1GLAKMT2AHDAC3
SCHEMBL5916713 0.98 EPHX1 (0.50) ACHEEPHX1GLAKMT2AHDAC3
SCHEMBL141826 0.95 ACHE (0.48) ACHEEPHX1GLAKMT2AHDAC3
Benzene SCHEMBL9001703 0.90 HDAC3 (0.49) ACHEEPHX1GLAKMT2AHDAC3
SCHEMBL3653026 0.87 KMT2A (0.50) ACHEEPHX1GLAKMT2AHDAC3
SCHEMBL16248012 0.86 ACHE (0.44) ACHEEPHX1GLAKMT2AHDAC3
SCHEMBL9452185 0.86 ACHE (0.58) ACHEEPHX1
SCHEMBL300412 0.86 ACHE (0.47) ACHEEPHX1GLAKMT2AHDAC3
SCHEMBL3477298 0.85 EPHX1 (0.59) ACHEEPHX1KMT2A
SCHEMBL27535929 0.85 ACHE (0.62) ACHEEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9090795-B2 Method for producing composite particles WACKER CHEMIE AG (DE) 2015-07-28 US claimed
US-8470120-B2 Free radical polymerization of an unsaturated monomer such as vinyl or acrylic ester, vinylaromatics, olefin, dienes or vinyl halides; adding organosilicon compound before or during the polymerization or before drying WACKER CHEMIE AG (DE) 2013-06-25 US claimed
EP-2178971-B1 SILANE MODIFIED ADDITIVES AND SILANE MODIFIED POLYMER COMPOUNDS WACKER CHEMIE AG (DE) 2012-03-07 EP claimed
EP-2265663-B1 METHOD FOR PRODUCING COMPOSITE PARTICLES WACKER CHEMIE AG (DE) 2011-10-12 EP claimed
US-20110201727-A1 SILANE-MODIFIED ADDITIVES AND SILANE-MODIFIED POLYMER COMPOUNDS WACKER CHEMIE AG 2011-08-18 US claimed
US-20110015340-A1 Method for Producing Composite Particles WACKER CHEMIE AG (DE) 2011-01-20 US claimed
EP-1940887-B1 SILANE-MODIFIED DISPERSION POWDER WACKER CHEMIE AG (DE) 2010-03-03 EP claimed
US-20080271848-A1 Silane-Modified Dispersion Powders WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2008-11-06 US claimed
US-9453124-B2 Modified composite particles WACKER CHEMIE AG (DE) 2016-09-27 US disclosed
US-9221717-B2 Silane-modified additives and silane-modified polymer compounds WACKER CHEMIE AG (DE) 2015-12-29 US disclosed
US-9090795-B2 Method for producing composite particles WACKER CHEMIE AG (DE) 2015-07-28 US disclosed
US-20130337266-A1 MODIFIED COMPOSITE PARTICLES WACKER CHEMIE AG (DE) 2013-12-19 US disclosed
US-8470120-B2 Free radical polymerization of an unsaturated monomer such as vinyl or acrylic ester, vinylaromatics, olefin, dienes or vinyl halides; adding organosilicon compound before or during the polymerization or before drying WACKER CHEMIE AG (DE) 2013-06-25 US disclosed
US-20110201727-A1 SILANE-MODIFIED ADDITIVES AND SILANE-MODIFIED POLYMER COMPOUNDS WACKER CHEMIE AG 2011-08-18 US disclosed
US-20110015340-A1 Method for Producing Composite Particles WACKER CHEMIE AG (DE) 2011-01-20 US disclosed
US-20080271848-A1 Silane-Modified Dispersion Powders WACKER POLYMER SYSTEMS GMBH & CO. KG (DE) 2008-11-06 US disclosed
US-20060247407-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) 2006-11-02 US disclosed
US-7057001-B2 Polymers with urea groups and silyl groups and production and use thereof HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2006-06-06 US disclosed
US-20050260401-A1 Polymers with urea groups and silyl groups and production and use thereof HENKEL AG & CO. KGAA (DE) 2005-11-24 US disclosed
WO-2002050020-A1 METHOD FOR PRODUCING ISOCYANATES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2002-06-27 WO disclosed