SCHEMBL16248012

SCHEMBL16248012

CCOC(=O)NCCC[Si](OC)(OCC)OCC

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.44
GLA P06280 1/20 0.41
KMT2A Q03164 1/20 0.41
EPHX1 P07099 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC4 P56524 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC7 Q8WUI4 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC10 Q969S8 1/20 0.40
HDAC11 Q96DB2 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
HDAC9 Q9UKV0 1/20 0.40
HDAC5 Q9UQL6 1/20 0.40
NCOR2 Q9Y618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141826 0.91 ACHE (0.48) ACHEGLAKMT2AEPHX1HDAC3
SCHEMBL139102 0.91 ACHE (0.48) ACHEGLAKMT2AEPHX1HDAC3
SCHEMBL3477710 0.90 EPHX1 (0.52) ACHEEPHX1
SCHEMBL7044336 0.88 GLA (0.39) ACHEGLAKMT2AEPHX1HDAC3
Benzene SCHEMBL9001703 0.87 HDAC3 (0.49) ACHEGLAKMT2AEPHX1HDAC3
SCHEMBL4637404 0.86 EPHX1 (0.35) ACHEKMT2AEPHX1HDAC3HDAC4
SCHEMBL300406 0.86 ACHE (0.47) ACHEGLAKMT2AEPHX1HDAC3
SCHEMBL6537039 0.86 EPHX1 (0.52) ACHEEPHX1
SCHEMBL300412 0.86 ACHE (0.47) ACHEGLAKMT2AEPHX1HDAC3
SCHEMBL19986490 0.85 ACHE (0.43) ACHEGLAKMT2AEPHX1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10604628-B2 Polymer and thermosetting composition containing same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2020-03-31 US disclosed
US-20170260330-A1 Novel Polymer and Thermosetting Composition Containing Same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2017-09-14 US disclosed
US-20170260330-A1 Novel Polymer and Thermosetting Composition Containing Same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. 2017-09-14 US disclosed
US-9695284-B2 Polymer and thermosetting composition containing same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2017-07-04 US disclosed
US-9695284-B2 Polymer and thermosetting composition containing same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2017-07-04 US disclosed
WO-2014186721-A1 NOVEL POLYMER AND THERMOSETTING COMPOSITION CONTAINING SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2014-11-20 WO disclosed
US-20140343199-A1 Novel Polymer and Thermosetting Composition Containing Same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2014-11-20 US disclosed
US-20140343199-A1 Novel Polymer and Thermosetting Composition Containing Same FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2014-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170260330-A1 Novel Polymer and Thermosetting Composition Containing Same INO80C, INCENP, PUF60 ACHE 3960/4885GLA 1780/4885KMT2A 2924/4885
US-10604628-B2 Polymer and thermosetting composition containing same PARG, INO80C, INCENP ACHE 3860/4885GLA 1723/4885KMT2A 2769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.