Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6921298 | 0.80 | ADORA2A (0.44) | KDM4EADORA2AADORA1F2CFD | |
| SCHEMBL1266435 | 0.79 | ADORA1 (0.50) | KDM4EADORA2AADORA1F2CFD | |
| SCHEMBL13853278 | 0.75 | ELANE (0.41) | KDM4EF2CFDC1RALDH1A1 | |
| SCHEMBL31163568 | 0.71 | NOS1 (0.42) | KDM4ELMNACYP1A2TSHRBLM | |
| SCHEMBL1218582 | 0.70 | GRIN2D (0.49) | KDM4EADORA2AADORA1GMNNLMNA | |
| SCHEMBL30980985 | 0.70 | GRIN2D (0.49) | KDM4EADORA2AADORA1GMNNLMNA | |
| SCHEMBL1522777 | 0.69 | PARP1 (0.53) | ADORA2AADORA1HSD17B10F2CFD | |
| SCHEMBL18306004 | 0.68 | ADORA2A (0.65) | KDM4EADORA2AADORA1GMNNLMNA | |
| SCHEMBL5369123 | 0.68 | KDM4E (0.50) | KDM4EADORA2AADORA1GMNNLMNA | |
| SCHEMBL5368416 | 0.67 | LMNA (0.53) | KDM4EADORA2AADORA1GMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069957-B | Prolyl hydroxylase inhibitors and uses thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |