Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3053989 | 0.79 | ALDH1A1 (0.80) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL30387868 | 0.76 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL24169274 | 0.76 | MAPT (1.00) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL14459434 | 0.76 | KMT2A (0.74) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL23539712 | 0.74 | MAPT (0.70) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9939658 | 0.73 | KMT2A (0.50) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL9924130 | 0.72 | DCUN1D1 (0.52) | MAPTALDH1A1MEN1KMT2AHTT | |
| Chlorobenzene SCHEMBL27823042 | 0.72 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL15531106 | 0.71 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL23336404 | 0.71 | P2RX1 (0.76) | MAPTALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279741-A | 4-phenyl-N- (phenyl) thiazol-2-amine derivatives and related compounds as Aryl Hydrocarbon Receptor (AHR) agonists for the treatment of, for example, angiogenesis-related disorders or inflammatory disorders | 医肯纳肿瘤学公司 | 2022-11-01 | — | — | CN | disclosed |