Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 6/20 | 0.52 |
| ▸ | UBE2M | P61081 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.44 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.43 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924226 | 0.93 | EPHX2 (0.53) | DCUN1D1UBE2MMAPTMEN1KMT2A | |
| SCHEMBL17206706 | 0.91 | DCUN1D1 (0.52) | DCUN1D1UBE2MMAPTMEN1KMT2A | |
| SCHEMBL9924131 | 0.90 | NPC1 (0.50) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9924262 | 0.89 | UBE2M (0.46) | DCUN1D1UBE2MMAPTMEN1KMT2A | |
| SCHEMBL17206619 | 0.89 | EPHX2 (0.48) | DCUN1D1UBE2MMAPTMEN1KMT2A | |
| SCHEMBL9924227 | 0.88 | EPHX2 (0.52) | DCUN1D1UBE2MMAPTMEN1KMT2A | |
| SCHEMBL9924260 | 0.83 | MEN1 (0.46) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9924214 | 0.83 | MEN1 (0.49) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL9924222 | 0.82 | CYP2D6 (0.44) | MEN1KMT2ALMNAEPHX2CYP2D6 | |
| SCHEMBL17206624 | 0.82 | CYP2D6 (0.44) | MEN1KMT2ALMNAEPHX2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |