Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 3/20 | 0.48 |
| ▸ | PLK1 | P53350 | 4/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 5/20 | 0.42 |
| ▸ | EGFR | P00533 | 7/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | ROS1 | P08922 | 1/20 | 0.38 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23606892 | 1.00 | MAPK10 (0.48) | MAPK10PLK1FGFR1FGFR2FGFR4 | |
| SCHEMBL23606893 | 0.89 | FGFR1 (0.51) | MAPK10PLK1FGFR1FGFR2FGFR4 | |
| SCHEMBL28600015 | 0.86 | MAPK10 (0.52) | MAPK10PLK1FGFR1FGFR2FGFR4 | |
| SCHEMBL30044163 | 0.79 | SLC2A1 (0.52) | PLK1FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL25139769 | 0.79 | SLC2A1 (0.52) | PLK1FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL25139771 | 0.78 | PLK1 (0.60) | PLK1FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL30043654 | 0.78 | PLK1 (0.60) | PLK1FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL23581156 | 0.78 | ALK (0.49) | MAPK10PLK1FGFR1FGFR2FGFR4 | |
| SCHEMBL23581181 | 0.77 | FGFR4 (0.52) | MAPK10FGFR1FGFR2FGFR4FGFR3 | |
| SCHEMBL21596379 | 0.76 | PLK1 (0.56) | PLK1FGFR1FGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12582654-B2 | Cyano-substituted pyridine and cyano-substituted pyrimidine compound and preparation method therefor and application thereof | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2026-03-24 | — | — | US | disclosed |
| EP-4083021-B1 | CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | BEIJING SCITECH MQ PHARMACEUTICALS LTD (CN) | 2025-07-02 | — | — | EP | disclosed |
| US-20230125046-A1 | CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) | 2023-04-20 | — | — | US | disclosed |
| EP-4083021-A1 | CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Beijing Scitech-MQ Pharmaceuticals Limited (CN) | 2022-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230125046-A1 | CYANO-SUBSTITUTED PYRIDINE AND CYANO-SUBSTITUTED PYRIMIDINE COMPOUND AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | FGFR4, FGFR1, WEE1 | MAPK10 289/4885PLK1 250/4885FGFR1 2/4885 |
| US-12582654-B2 | Cyano-substituted pyridine and cyano-substituted pyrimidine compound and preparation method therefor and application thereof | FGFR4, FGFR3, FGFR1 | MAPK10 1917/4885PLK1 469/4885FGFR1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.