SCHEMBL300453

SCHEMBL300453

C=CCc1ccc2c(c1CC=C)Cc1ccccc1-2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.45
ADRA1D P25100 1/20 0.39
ADRA1A P35348 1/20 0.39
ADRA1B P35368 1/20 0.39
GABRA1 P14867 1/20 0.38
GABRB2 P47870 1/20 0.38
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SRD5A2 P31213 1/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
PGR P06401 1/20 0.33
HTR7 P34969 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28594775 0.87 PNMT (0.40) PNMTADRA1DADRA1AADRA1BGABRA1
SCHEMBL28664098 0.85 PNMT (0.38) PNMTADRA1DADRA1AADRA1BNPC1
SCHEMBL9578161 0.83 PNMT (0.44) PNMTADRA1DADRA1AADRA1BNPC1
SCHEMBL252161 0.82 PNMT (0.62) PNMTADRA1DADRA1AADRA1BGABRA1
SCHEMBL30275939 0.80 PNMT (0.38) PNMTADRA1DADRA1AADRA1BNPC1
SCHEMBL17351165 0.79 PNMT (0.43) PNMTADRA1DADRA1AADRA1BNPC1
SCHEMBL28956620 0.79 PNMT (0.46) PNMTADRA1DADRA1AADRA1BNPC1
SCHEMBL21295457 0.76 PNMT (0.46) PNMTADRA1DADRA1AADRA1BGABRA1
SCHEMBL21295463 0.76 PNMT (0.43) PNMTADRA1DADRA1AADRA1BGABRA1
SCHEMBL29406544 0.76 PNMT (0.40) PNMTADRA1DADRA1AADRA1BNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10109796-B2 Methods of applying polymers to surfaces and surfaces coated by polymers SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2018-10-23 US claimed
US-9398927-B2 Medical implant SYNERGY BIOSURGICAL AG (CH) 2016-07-26 US claimed
EP-2181935-B1 Method of manufacturing an anti-static container SCHNEIDER EKKEHARD DIPL-ING (DE) 2016-06-22 EP claimed
US-8741392-B2 Anodically assisted chemical etching of conductive polymers and polymer composites INTEGRAN TECHNOLOGIES, INC. (CA) 2014-06-03 US claimed
EP-2654589-A1 KIT FOR IMPLANTING HEAT DEFORMABLE FIXATION ELEMENTS OF DIFFERENT SIZES Synthes GmbH (CH) 2013-10-30 EP claimed
WO-2012087426-A1 KIT FOR IMPLANTING HEAT DEFORMABLE FIXATION ELEMENTS OF DIFFERENT SIZES SYNTHES USA, LLC (US) 2012-06-28 WO claimed
US-20120157977-A1 Kit for Implanting Heat Deformable Fixation Elements of Different Sizes DEPUY SPINE, LLC 2012-06-21 US claimed
EP-2438220-A1 ANODICALLY ASSISTED CHEMICAL ETCHING OF CONDUCTIVE POLYMERS AND POLYMER COMPOSITES Integran Technologies Inc. (CA) 2012-04-11 EP claimed
US-20100311901-A1 ARAMID FILLED POLYIMIDES HAVING ADVANTAGEOUS THERMAL EXPANSION PROPERTIES, AND METHODS RELATING THERETO E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-12-09 US claimed
WO-2010139051-A1 ANODICALLY ASSISTED CHEMICAL ETCHING OF CONDUCTIVE POLYMERS AND POLYMER COMPOSITES INTEGRAN TECHNOLOGIES, INC. (CA) 2010-12-09 WO claimed
US-20060068211-A1 Low temperature polyimide adhesive compositions and methods relating thereto DUPONT ELECTRONICS, INC. 2006-03-30 US claimed
EP-1638666-A1 CONDUCTING GAS PURIFICATION FILTER AND FILTER ASSEMBLY NUTSOS, Mikael (SE) 2006-03-29 EP claimed
WO-2006031411-A2 A CONDUCTIVE LITHOGRAPHIC POLYMER MIXTURE AND METHOD OF MAKING DEVICES USING SAME INTEL CORPORATION (US) 2006-03-23 WO claimed
US-20060051707-A1 Conductive lithographic polymer and method of making devices using same INTEL CORPORATION 2006-03-09 US claimed
EP-1531657-A1 Multi-layer substrates having at least two dissimilar polyimide layers and a conductive layer, useful for electronics-type applications, and compositions relating thereto E. I. du Pont de Nemours and Company (US) 2005-05-18 EP claimed
US-20050100719-A1 Vaiations in glass transition temperature between layers; electroconductive layer DUPONT ELECTRONICS, INC. 2005-05-12 US claimed
WO-2004096413-A1 CONDUCTING GAS PURIFICATION FILTER AND FILTER ASSEMBLY NUTSOS MIKAEL (SE) 2004-11-11 WO claimed
EP-1424352-A1 Low temperature polymide adhesive compositions and methods relating thereto E.I.Du pont de nemours and company (US) 2004-06-02 EP claimed
US-20040099374-A1 Low temperature polyimide adhesive compositions and methods relating thereto DUPONT ELECTRONICS, INC. 2004-05-27 US claimed
US-20020093283-A1 Luminescent device and method of manufacturing same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2002-07-18 US claimed