SCHEMBL252161

SCHEMBL252161

C=CCc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.62
GABRA1 P14867 2/20 0.53
GABRB2 P47870 2/20 0.53
DRD2 P14416 1/20 0.45
DRD4 P21917 1/20 0.45
DRD3 P35462 1/20 0.45
ADRA1D P25100 1/20 0.42
ADRA1A P35348 1/20 0.42
ADRA1B P35368 1/20 0.42
AKR1B1 P15121 1/20 0.42
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
HTR7 P34969 1/20 0.37
HTR2B P41595 1/20 0.37
KDM4E B2RXH2 2/20 0.36
LMNA P02545 2/20 0.36
HPGD P15428 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL123076 0.83 PNMT (0.62) PNMTGABRA1GABRB2DRD2DRD4
SCHEMBL300453 0.82 PNMT (0.45) PNMTGABRA1GABRB2DRD2DRD4
SCHEMBL28661210 0.81 PNMT (0.55) PNMTGABRA1GABRB2DRD2DRD4
SCHEMBL9781384 0.80 AKR1B1 (0.61) PNMTGABRA1GABRB2AKR1B1LMNA
SCHEMBL4989855 0.80 PNMT (0.68) PNMTDRD2DRD4DRD3NPC1
SCHEMBL499898 0.80 PNMT (0.68) PNMTDRD2DRD4DRD3ADRA1D
SCHEMBL10774995 0.80 PNMT (0.63) PNMTGABRA1GABRB2DRD2DRD4
SCHEMBL28426322 0.80 PNMT (0.58) PNMTGABRA1GABRB2DRD2DRD4
SCHEMBL17186646 0.80 PNMT (0.58) PNMTGABRA1GABRB2DRD2DRD4
SCHEMBL21295457 0.80 PNMT (0.46) PNMTGABRA1GABRB2DRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 875 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115716787-B Alkyl fluorene small molecular compound and preparation method and application thereof 天津大学 2024-02-13 CN claimed
CN-117330681-A Fine separation method of crude oil and polycyclic aromatic hydrocarbons with different ring numbers in sedimentary organic matters based on chromatographic column 中国石油大学(北京) 2024-01-02 CN claimed
CN-116622040-A Fluorene and pyrrolo-dithiophene-based polymer and preparation method and application thereof 山西大学 2023-08-22 CN claimed
CN-116470245-A Composition containing small molecule additives for improving safety and performance of high voltage battery 阿米恩科斯公司 2023-07-21 CN claimed
CN-115716787-A Alkyl fluorene micromolecule compound and preparation method and application thereof 天津大学 2023-02-28 CN claimed
CN-114720596-B Separation method of crude oil components rich in aromatic hydrocarbon 中国科学院兰州化学物理研究所 2023-01-10 CN claimed
CN-113817090-B Triterpyridine-based transition metal ion fluorescence chemical sensor and preparation method thereof 青岛科技大学 2022-10-25 CN claimed
CN-115109027-A Degradable fluorescent molecule for photodynamic therapy, preparation method and application 江汉大学 2022-09-27 CN claimed
CN-113817090-A Triterpyridine-based transition metal ion fluorescence chemical sensor and preparation method thereof 青岛科技大学 2021-12-21 CN claimed
CN-113549196-A Fluorenyl conjugated polymer and preparation method of electric storage device thereof 黑龙江大学 2021-10-26 CN claimed
CN-1587345-A Comb type high molecular luminous material and its preparing method UNIV FUDAN (CN) 2005-03-02 CN claimed
US-20040230021-A1 Mono-, oligo- and polymers comprising dithienothiophene and aryl groups FLEXENABLE TECHNOLOGY LIMITED (GB) 2004-11-18 US claimed
EP-1477504-A1 Mono-, oligo- and polymers comprising dithienotiophene and aryl groups MERCK PATENT GmbH (DE) 2004-11-17 EP claimed
US-6814887-B2 HIGH MOLECULAR WEIGHT COMPOUND, MATERIAL EMITTING LIGHT BY APPLYING AN ELECTRIC FIELD, SOLVENT; HIGHER RESPONSE SPEED THAN LIQUID-CRYSTAL DISPLAY HITACHI, LTD. (JP) 2004-11-09 US claimed
CN-1538788-A Method for manufacturing polarized polymer electroluminescent device 胜园科技股份有限公司 2004-10-20 CN claimed
CN-1516529-A Electroluminescenjt tube illuminant line and its production method 殷峥凯 2004-07-28 CN claimed
US-20040137271-A1 Blue electroluminescent polymer and organo-electroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2004-07-15 US claimed
CN-1483783-A Electrolumineseence bule light polymer and organic electroluminescence device using same ����SDI��ʽ���� 2004-03-24 CN claimed
CN-1438254-A Polyalkyl-fluorene conjugated polymer and use UNIV SICHUAN (CN) 2003-08-27 CN claimed
US-20030098444-A1 Organic-electroluminescence device, process for its production and organic-electroluminescence display system SAMSUNG DISPLAY CO., LTD. (KR) 2003-05-29 US claimed