Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | FTO | Q9C0B1 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300176 | 0.91 | CYP3A4 (0.45) | CYP3A4FTOMEN1KMT2AMAPT | |
| SCHEMBL275739 | 0.87 | CYP3A4 (0.60) | CYP3A4FTOMEN1KMT2AMAPT | |
| SCHEMBL13069672 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2AMAPTHTTHPGD | |
| SCHEMBL21440424 | 0.84 | CYP3A4 (0.61) | CYP3A4FTOMEN1KMT2AMAPT | |
| SCHEMBL31150744 | 0.84 | CYP3A4 (0.64) | CYP3A4FTOMEN1KMT2AMAPT | |
| SCHEMBL29369814 | 0.84 | CYP3A4 (0.64) | CYP3A4FTOMEN1KMT2AMAPT | |
| SCHEMBL52075 | 0.84 | CYP3A4 (0.64) | CYP3A4FTOMEN1KMT2AMAPT | |
| SCHEMBL9104715 | 0.82 | CYP3A4 (0.59) | CYP3A4FTOMEN1KMT2AMAPT | |
| SCHEMBL10347973 | 0.82 | CYP3A4 (0.61) | CYP3A4FTOMEN1KMT2AMAPT | |
| SCHEMBL11882058 | 0.82 | CYP3A4 (0.52) | CYP3A4FTOMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134017-B1 | Compound and use thereof | RIKEN (JP) | 2012-03-13 | — | — | US | disclosed |