SCHEMBL13069672

SCHEMBL13069672

CCN(CC)c1ccc2c(c1)Oc1cc(N(CC)CC)ccc1C2(O)c1ccccc1C=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
CA12 O43570 5/20 0.43
CA9 Q16790 5/20 0.43
CA1 P00915 4/20 0.43
CA2 P00918 4/20 0.43
CA3 P07451 4/20 0.43
CA4 P22748 4/20 0.43
CA6 P23280 4/20 0.43
CA5A P35218 4/20 0.43
CA7 P43166 4/20 0.43
CA13 Q8N1Q1 4/20 0.43
CA14 Q9ULX7 4/20 0.43
CA5B Q9Y2D0 4/20 0.43
MAPT P10636 8/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
KDM4E B2RXH2 4/20 0.41
HPGD P15428 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300458 0.86 CYP3A4 (0.48) ALDH1A1L3MBTL1CA12CA9CA1
SCHEMBL13135701 0.84 ALDH1A1 (0.51) ALDH1A1L3MBTL1CA12CA9CA1
SCHEMBL20369125 0.83 ALDH1A1 (0.44) ALDH1A1L3MBTL1CA12CA9CA1
SCHEMBL11796224 0.81 MEN1 (0.52) ALDH1A1L3MBTL1CA12CA9CA1
SCHEMBL19494876 0.81 ALDH1A1 (0.51) ALDH1A1L3MBTL1CA12CA9CA1
SCHEMBL21440425 0.77 CA12 (0.39) ALDH1A1L3MBTL1CA12CA9CA1
SCHEMBL12939881 0.77 FTO (0.50) ALDH1A1MAPTMEN1KMT2AHPGD
SCHEMBL300176 0.77 CYP3A4 (0.45) ALDH1A1L3MBTL1CA12CA9CA1
SCHEMBL20369033 0.77 ALDH1A1 (0.39) ALDH1A1L3MBTL1CA12CA9CA1
SCHEMBL19495100 0.77 ALDH1A1 (0.52) ALDH1A1L3MBTL1CA12CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2144918-B1 FUNCTIONALIZED NANOPARTICLES BASF SE (DE) 2010-11-17 EP disclosed