Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 5/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574305 | 1.00 | PDE4A (0.46) | PDE4APDE4CPDE4DADORA2AADORA1 | |
| SCHEMBL26685340 | 0.89 | PDE4A (0.46) | PDE4APDE4CPDE4DADORA2AADORA1 | |
| SCHEMBL12679145 | 0.83 | ALDH1A1 (0.37) | PDE4APDE4CPDE4DADORA2AADORA1 | |
| SCHEMBL14548353 | 0.80 | PDE4A (0.34) | PDE4APDE4CPDE4DADORA2AADORA1 | |
| SCHEMBL26685365 | 0.78 | PDE4A (0.37) | PDE4APDE4CPDE4DADORA2AADORA1 | |
| SCHEMBL31570171 | 0.78 | PDE4A (0.37) | PDE4APDE4CPDE4DADORA2AADORA1 | |
| SCHEMBL1396872 | 0.77 | PDE4A (0.48) | PDE4APDE4CPDE4DADORA2AADORA1 | |
| SCHEMBL2749007 | 0.77 | PDE4A (0.48) | PDE4APDE4CPDE4DADORA2AADORA1 | |
| SCHEMBL18133374 | 0.73 | HSD11B1 (0.45) | PDE4APDE4CPDE4DADORA2AADORA1 | |
| SCHEMBL18890302 | 0.71 | PDE4A (0.39) | PDE4APDE4CPDE4DADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119998278-A | Compounds and uses thereof | 福宏治疗公司 | 2025-05-13 | — | — | CN | disclosed |
| EP-4329889-A1 | IL4I1 INHIBITORS AND METHODS OF USE | Merck Sharp & Dohme LLC (US) | 2024-03-06 | — | — | EP | disclosed |
| WO-2022232333-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2022-11-03 | — | — | WO | disclosed |