SCHEMBL30047434

SCHEMBL30047434

OC[C@H]1O[C@@H](n2ncc3c(NO)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADA P00813 1/20 0.52
▸ TP53 P04637 1/20 0.52
▸ STAT6 P42226 1/20 0.52
▸ HIF1A Q16665 1/20 0.52
▸ ATG7 O95352 1/20 0.51
▸ ADK P55263 6/20 0.49
▸ DOT1L Q8TEK3 1/20 0.48
▸ DCLK1 O15075 1/20 0.48
▸ DAPK3 O43293 1/20 0.48
▸ DYRK3 O43781 1/20 0.48
▸ CDK1 P06493 1/20 0.48
▸ ROS1 P08922 1/20 0.48
▸ RPS6KB1 P23443 1/20 0.48
▸ CDK2 P24941 1/20 0.48
▸ FLT3 P36888 1/20 0.48
▸ CSNK1A1 P48729 1/20 0.48
▸ CSNK1D P48730 1/20 0.48
▸ CLK2 P49760 1/20 0.48
▸ IRAK1 P51617 1/20 0.48
▸ CDK5 Q00535 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29601078 0.89 ATG7 (0.53) ADASTAT6HIF1AATG7ADK
SCHEMBL29600893 0.89 ADK (0.58) ADAATG7ADK
SCHEMBL29325559 0.85 ADA (0.54) ADASTAT6ATG7ADKDOT1L
SCHEMBL29323419 0.85 ADA (0.54) ADASTAT6ATG7ADKDOT1L
SCHEMBL11672972 0.85 ADA (0.54) ADASTAT6ATG7ADKDOT1L
SCHEMBL6672454 0.85 ADA (0.54) ADASTAT6ATG7ADKDOT1L
SCHEMBL6671707 0.85 ADA (0.54) ADASTAT6ATG7ADKDOT1L
SCHEMBL11327761 0.85 ADA (0.54) ADASTAT6ATG7ADKDOT1L
SCHEMBL11207738 0.85 ADA (0.54) ADASTAT6ATG7ADKDOT1L
SCHEMBL8975931 0.84 ADK (0.71) ADKSMN1; SMN2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114450265-B Cationic lipids and uses thereof 菲克特生物科学股份有限公司 2024-12-24 — — CN claimed
EP-4705273-A2 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS Factor Bioscience Inc. (US) 2026-03-11 — — EP disclosed
EP-4673226-A1 RNA-BASED INHIBITORS OF TRNA MODIFYING ENZYMES Yale University (US) 2026-01-07 — — EP disclosed
EP-4673165-A1 INTERLEUKIN-2 AND INTERLEUKIN-12 FOR CANCER THERAPY KRYSTAL BIOTECH, INC. (US) 2026-01-07 — — EP disclosed
WO-2024182707-A9 INTERLEUKIN-2 AND INTERLEUKIN-12 FOR CANCER THERAPY Krystal Biotech, Inc. (US) 2024-12-05 — — WO disclosed
WO-2024229032-A2 MULTIVALENT IONIZABLE LIPID DELIVERY SYSTEMS FACTOR BIOSCIENCE INC. (US) 2024-11-07 — — WO disclosed
EP-4429641-A1 BIOMARKERS OF MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES STRM.Bio Incorporated (US) 2024-09-18 — — EP disclosed
WO-2024182707-A1 INTERLEUKIN-2 AND INTERLEUKIN-12 FOR CANCER THERAPY Krystal Biotech, Inc. (US) 2024-09-06 — — WO disclosed
WO-2024182719-A1 RNA-BASED INHIBITORS OF TRNA MODIFYING ENZYMES YALE UNIVERSITY (US) 2024-09-06 — — WO disclosed
EP-4329799-A1 MESSENGER RNA THERAPEUTICS AND COMPOSITIONS Greenlight Biosciences, Inc. (US) 2024-03-06 — — EP disclosed
WO-2023205424-A2 LIPID COMPOSITIONS AND METHODS FOR NUCLEIC ACID DELIVERY GREENLIGHT BIOSCIENCES, INC. (US) 2023-10-26 — — WO disclosed
EP-4182332-A1 NUCLEIC ACID THERAPEUTICS FOR GENETIC DISORDERS Greenlight Biosciences, Inc. (US) 2023-05-24 — — EP disclosed
WO-2023086590-A1 METHODS RELATED TO MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES STRM.BIO INCORPORATED (US) 2023-05-19 — — WO disclosed
WO-2023086595-A1 BIOMARKERS OF MEGAKARYOCYTE-DERIVED EXTRACELLULAR VESICLES STRM.BIO INCORPORATED (US) 2023-05-19 — — WO disclosed
WO-2022232687-A1 MESSENGER RNA THERAPEUTICS AND COMPOSITIONS GREENLIGHT BIOSCIENCES, INC. (US) 2022-11-03 — — WO disclosed
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