SCHEMBL300475

SCHEMBL300475

O=C(NN1CCCCC1)Oc1nn(-c2ccc(Cl)cc2Cl)c2c1CCCCC2Cc1cccc(F)c1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 9/20 0.42
CNR1 P21554 7/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL300711 0.94 CNR2 (0.44) CNR2CNR1
SCHEMBL300689 0.94 CNR1 (0.40) CNR2CNR1
SCHEMBL300468 0.88 FAAH (0.44) CNR2CNR1
SCHEMBL176761 0.88 CNR2 (0.54) CNR2CNR1
SCHEMBL176572 0.82 CNR2 (0.50) CNR2CNR1
SCHEMBL176408 0.82 CNR2 (0.57) CNR2CNR1
SCHEMBL3470418 0.81 CNR2 (0.41) CNR2CNR1
SCHEMBL300695 0.81 CNR1 (0.46) CNR2CNR1
SCHEMBL176432 0.80 CNR2 (0.57) CNR2CNR1
SCHEMBL176413 0.79 CNR2 (0.53) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937259-B1 HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2011-11-23 EP claimed