Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.40 |
| ▸ | CNR2 | P34972 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300475 | 0.94 | CNR2 (0.42) | CNR1CNR2 | |
| SCHEMBL176572 | 0.89 | CNR2 (0.50) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL300711 | 0.88 | CNR2 (0.44) | CNR1CNR2 | |
| SCHEMBL300468 | 0.86 | FAAH (0.44) | CNR1CNR2 | |
| SCHEMBL176539 | 0.82 | CNR2 (0.52) | CNR1CNR2KDM4EMEN1CYP1A2 | |
| SCHEMBL176761 | 0.82 | CNR2 (0.54) | CNR1CNR2 | |
| SCHEMBL3470418 | 0.80 | CNR2 (0.41) | CNR1CNR2 | |
| SCHEMBL300695 | 0.80 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL257721 | 0.78 | CNR2 (0.46) | CNR1CNR2 | |
| SCHEMBL176413 | 0.77 | CNR2 (0.53) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |