Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.51 |
| ▸ | CNR1 | P21554 | 9/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL300508 | 0.93 | CNR2 (0.46) | CNR2CNR1 | |
| SCHEMBL300646 | 0.86 | CNR2 (0.56) | CNR2CNR1 | |
| SCHEMBL4712149 | 0.81 | TAS1R3 (0.41) | CNR2CNR1 | |
| SCHEMBL4714049 | 0.80 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL300365 | 0.80 | CNR2 (0.41) | CNR2CNR1APPPSEN1PSEN2 | |
| SCHEMBL4709016 | 0.79 | CNR2 (0.40) | CNR2CNR1 | |
| SCHEMBL300736 | 0.79 | CNR2 (0.43) | CNR2CNR1 | |
| SCHEMBL300671 | 0.79 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL300538 | 0.79 | CNR2 (0.39) | CNR2CNR1 | |
| SCHEMBL300498 | 0.78 | PTGS2 (0.42) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937259-B1 | HEXAHYDRO-CYCLOHEPTAPYRAZOLE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-11-23 | — | — | EP | claimed |