SCHEMBL30050466

SCHEMBL30050466

C(=C/c1ccc2nc[nH]c2c1)\c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IP6K1 Q92551 5/20 0.63
IP6K3 Q96PC2 2/20 0.63
IP6K2 Q9UHH9 1/20 0.63
HDAC1 Q13547 1/20 0.60
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
HTT P42858 2/20 0.50
HPGD P15428 2/20 0.50
RAB9A P51151 1/20 0.50
TAAR1 Q96RJ0 1/20 0.49
PRKCI P41743 1/20 0.49
ESR1 P03372 1/20 0.48
MAPT P10636 2/20 0.47
RAD52 P43351 1/20 0.47
CTNNB1 P35222 1/20 0.47
WNT3A P56704 1/20 0.47
QPCT Q16769 1/20 0.46
QPCTL Q9NXS2 1/20 0.46
POLB P06746 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10817405 1.00 IP6K1 (0.63) IP6K1IP6K3IP6K2HDAC1ALDH1A1
SCHEMBL14972936 1.00 IP6K1 (0.63) IP6K1IP6K3IP6K2HDAC1ALDH1A1
SCHEMBL10817399 0.86 IP6K1 (0.59) IP6K1IP6K3IP6K2HDAC1ALDH1A1
(Z)-1,2-Diphenylethene SCHEMBL29239809 0.84 TAAR1 (0.53) IP6K1IP6K3IP6K2HDAC1ALDH1A1
(Z)-1,2-Diphenylethene SCHEMBL10948499 0.84 TAAR1 (0.53) IP6K1IP6K3IP6K2HDAC1ALDH1A1
(Z)-1,2-Diphenylethene SCHEMBL10948488 0.84 TAAR1 (0.53) IP6K1IP6K3IP6K2HDAC1ALDH1A1
SCHEMBL710124 0.79 IP6K1 (0.56) IP6K1IP6K3IP6K2HDAC1ALDH1A1
SCHEMBL710123 0.79 IP6K1 (0.56) IP6K1IP6K3IP6K2HDAC1ALDH1A1
SCHEMBL1418704 0.77 HDAC1 (0.56) HDAC1ALDH1A1KDM4ESMN1; SMN2HTT
SCHEMBL4236820 0.77 PRKCI (0.53) HDAC1ALDH1A1KDM4ESMN1; SMN2HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250346562-A1 OCT4 HIGH-SELECTIVITY ACTIVATOR IREGENE THERAPEUTICS LTD (CN) 2025-11-13 US disclosed
CN-115572285-B OCT4 high-selectivity activator 武汉睿健医药科技有限公司 2024-10-29 CN disclosed
EP-4361131-A1 OCT4 HIGH-SELECTIVITY ACTIVATOR Iregene Therapeutics Ltd (CN) 2024-05-01 EP disclosed
CN-115572256-A OCT4 high selectivity activator 武汉睿健医药科技有限公司 2023-01-06 CN disclosed
CN-115572285-A OCT4 high selectivity activator 武汉睿健医药科技有限公司 2023-01-06 CN disclosed
WO-2022266794-A1 OCT4 HIGH-SELECTIVITY ACTIVATOR 武汉睿健医药科技有限公司 2022-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346562-A1 OCT4 HIGH-SELECTIVITY ACTIVATOR POU2F1, POU5F1, POU2F2 IP6K1 2031/4885IP6K3 2753/4885IP6K2 2159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.