Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30050124 | 0.88 | PDE7A (0.52) | L3MBTL1GRM5ALDH1A1MAPTGAA | |
| SCHEMBL29888172 | 0.84 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1MAPTHTTGAA | |
| SCHEMBL24570249 | 0.84 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1MAPTHTTGAA | |
| SCHEMBL22076853 | 0.81 | ATM (0.45) | ALDH1A1MAPTHTTGAAMAPK1 | |
| SCHEMBL31693509 | 0.81 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTHTTGAA | |
| SCHEMBL30050568 | 0.81 | MAPT (0.48) | L3MBTL1ALDH1A1MAPTHTTGAA | |
| SCHEMBL30050403 | 0.80 | GRM5 (0.41) | L3MBTL1GRM5ALDH1A1MAPTHTT | |
| SCHEMBL30050598 | 0.80 | GRM5 (0.39) | L3MBTL1GRM5ALDH1A1MAPTHTT | |
| SCHEMBL23959239 | 0.79 | GRM5 (0.44) | GRM5ALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL30051312 | 0.79 | GRM5 (0.44) | GRM5ALDH1A1MAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025202889-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2025-10-02 | — | — | WO | disclosed |
| WO-2022269531-A1 | HER2 MUTATION INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2022-12-29 | — | — | WO | disclosed |